Journal of global antimicrobial resistanceAnti-Bacterial Agentsbeta-LactamsHumansPseudomonas aeruginosaMicrobial Sensitivity Tests
Pharmacokinetic/pharmacodynamic targets of ß-lactams associated with bacterial killing and suppression of the resistance emergence in the hollow fiber infection model: A systematic review.
Charles Baulier, Marion Giry, Manuel Etienne, Julien Kallout, Kévin Alexandre
Published: 202510.1016/j.jgar.2025.10.009
Abstract
INTRODUCTION: The hollow-fibre infection model (HFIM) is an in vitro model used to study pharmacokinetic/pharmacodynamic (PK/PD) interactions between antibiotics and bacteria. However, its external validity remains poorly assessed. This study aimed t…
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