Journal of ethnopharmacologyAnimalsCell ProliferationMonoterpenesRenal InsufficiencyChronic
Paeoniflorin enhances tubular repair by promoting dihydroorotate dehydrogenase-dependent epithelial cell proliferation in cisplatin-induced chronic kidney disease.
Cai-Wei Qiu, Hong-Wei Su, Jia-Shun Mao, Wei Wei, Jian-Qin Liu, Ying-Lan Liang, Hai-Long Yu, Shang-Jin Li, Ying Yang, Xiu Yang
Published: 202610.1016/j.jep.2025.121129
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Repeated low-dose cisplatin (RLDC) impairs tubule repair and promotes chronic kidney disease (CKD). Paeoniae Radix Rubra (Chishao in Chinese) is the dried root of Paeonia lactiflora Pall. or Paeonia veitchii Lynch, whi…
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