Journal of ethnopharmacology
Therapeutic potential of Dahuang Mudan Decoction for severe acute pancreatitis: targeting oxidative stress and MAPK pathways through network pharmacology and experimental verification1.
Lifang Duan, Ying Luo, Chenru Shang, Xin Cao, Xin Chen, Zhangli Yan, Xiaofan Xu, Jianwei Fan, Hong Zhang
Published: 202510.1016/j.jep.2025.121116
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Acute pancreatitis (AP) is an inflammatory disease caused by the premature activation of digestive enzymes, leading to pancreatic self-digestion. In about 20 % of cases, AP progresses to severe acute pancreatitis (SAP)…
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