Journal of ethnopharmacologyAnimalsZebrafishMiceRAW 264.7 CellsFerroptosis
Blockade of GPX4-mediated ferroptosis underlies the protective effect of Forsythiae Fructus water extract against poly(I:C)-induced inflammation.
Xindeng Guo, Bing Chen, Zhixian Su, Xia Cao, Lingna Dai, Zibin Lu, Zhiqing Liang, Li Jiang, Huihui Cao, Xiangdong Chen, Yunguang Hu, Linzhong Yu, Hua Lu, Junshan Liu
Published: 202610.1016/j.jep.2025.121076
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Forsythiae Fructus is a widely used traditional Chinese medicine commonly employed in the treatment of inflammation-related diseases. However, its underlying anti-inflammatory mechanisms remain incompletely elucidated.…
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