Journal of ethnopharmacologyAnimalsAtractylodesFatiguePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaMale
Atractylodes macrocephala Koidz. water extract alleviates exercise-induced fatigue by activating mitochondrial biogenesis via the PGC-1α/NRF1/TFAM axis.
Guowei Ying, Jingjing Yu, Lin Jiao, Jie Liang, Zhangyun Wu, Binhui Pan, Su Gao, Suhong Chen, Guiyuan Lv
Published: 202610.1016/j.jep.2025.121053
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: In Traditional Chinese Medicine (TCM), Atractylodes macrocephala Koidz. (Baizhu) is a fundamental herb for fortifying the spleen and replenishing qi, specifically used to treat syndromes characterized by weakness, and…
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