Journal of ethnopharmacologyAnimalsLignansNF-E2-Related Factor 2FerroptosisSignal Transduction
Sesamin promotes the survival of skin flaps in rats by inhibiting ferroptosis through the Nrf2/SLC7A11/GPX4 signaling pathway.
Jialong Yang, Hebin Pan, Zhigang Bian, Yiran Wang, Qingyu Chen, Sihan Chen, Kai Chen, Weilong Song, Panshen Xu, An Wang, Jiapeng Deng, Dingsheng Lin
Published: 202610.1016/j.jep.2025.120938
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Skin flaps are widely used in surgery yet remain prone to distal necrosis, making improved survival a significant clinical goal. Sesamin, the primary bioactive component of traditional Chinese medicines Sesamum indicum…
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