Journal of ethnopharmacologyHumansHepatitis B virusOrganic Anion TransportersSodium-DependentSymporters
Novel mechanism of Guizhi Jia Huangqi decoction disrupting HBV lifecycle via cAMP/PKC/PKB axis beyond NTCP blockade.
Shenghao Li, Liyuan Hao, Fei Yu, Qing Peng, Na Li, Xiaoyu Hu
Published: 202610.1016/j.jep.2025.120885
Abstract
BACKGROUND AND PURPOSE: The eradication of covalently closed circular DNA (cccDNA) remains the primary obstacle to a functional cure for chronic hepatitis B virus (HBV) infection. While the entry inhibitor Myrcludex B, which targets the sodium tauroc…
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