Jieyu I formula and its primary component quercetin alleviate anxiety by modulating neuroregeneration and inflammation via the calcium signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: Jieyu I formula(JY-Ⅰ) was modified from SiNi San, and its anti-inflammatory and neuroprotective effects were investigated in preliminary studies. However, its potential mechanism of action in interfering with anxiety i…

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