Journal of ethnopharmacologyAnimalsFemaleMitophagyQuercetinSignal Transduction
Quercetin ameliorates diminished ovarian reserve via modulating intestinal BNIP3/dct-1-mediated mitophagy and subsequently activating the ovarian TGF-β signaling pathway.
Xian Xiao, Mian Zheng, Ying Zhao, Kaili Huang, Yuqing Shi, Yibo Ren, Linlin Chen, Jia Sun, Ran Ye, Zihui Zheng, Qinli Ruan
Published: 202610.1016/j.jep.2025.120736
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Diminished ovarian reserve (DOR) is one of the most important reasons for decreasing fertility. Quercetin, a phytochemical, widely exists in food and natural Chinese herbs and can increase female fertility. However, ho…
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