Journal of ethnopharmacologyMyeloid-Derived Suppressor CellsTumor MicroenvironmentCarcinomaNon-Small-Cell LungAnimals
Wu-wei-zi decoction reshapes the tumor immune microenvironment by targeting the IL-6/CD73 axis in myeloid-derived suppressor cells to inhibit non-small cell lung cancer.
Ming-Xi Liu, Lin Su, Xiao-Wen Zhu, Yang-Zhuangzhuang Zhu, Xiao Chen, Xiao-Yu Wang, Xue-Wei Yan, Xiao-Wen Wu, Fei Zhang, Chun-Pu Zou, Zi-Hang Xu
Published: 202610.1016/j.jep.2025.120727
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Wu-wei-zi decoction (WWZ) is a clinically utilized classical herbal formula for non-small cell lung cancer (NSCLC). Nevertheless, the underlying mechanism of WWZ-treated lung cancer that is still unknown requires furth…
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