Effects and mechanism of berberine in ameliorating microglia-mediated hypothalamic inflammation by downregulating the MAPK and NF-κB pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: Berberine (BBR), an isoquinoline alkaloid found in several plants, including Coptis chinensis, Phellodendron amurense, and various Berberis species, has been traditionally used to treat excessive thirst, abdominal dist…

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