Journal of controlled release : official journal of the Controlled Release Society
Dual-biomimetic Nanodecoys reprogram cardiac macrophages by suppressing STING signaling for heart repair.
Peng Wang, Ruobing Li, Jinjin Ni, Duanbin Li, Mei Hua Ting, Kai Ma, Guosheng Fu, Junbo Ge, Shenggang Zhao, Wenbin Zhang, Ning Zhang, Xianglan Liu
Published: 202610.1016/j.jconrel.2026.114647
Abstract
Myocardial infarction (MI) initiates sterile inflammation through the release of cytosolic DNA from necrotic cardiomyocytes, which aberrantly activates the cGAS-STING pathway in infiltrating macrophages and drives their polarization toward a pro-infl…
Preview only. Read the full abstract at the source