Journal of controlled release : official journal of the Controlled Release Society
An on-site cascading vaccine breaks tumor immune evasion and elicits systemic immunity.
Xianzhou Huang, Lu Li, Shuzhen Zheng, Guixia Wei, Yixi Wang, Xinchao Li, Changyang Gong, Wenmei Li, Yanjie You
Published: 202610.1016/j.jconrel.2026.114641
Abstract
Tumor cells evade immunosurveillance through a defense system conceptualized as camouflage, coercion, and cytoprotection. Therapeutic success requires simultaneous targeting of them all to restore antitumor immunosurveillance. Furthermore, the induct…
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