Journal of controlled release : official journal of the Controlled Release SocietyAnimalsCalixarenesGuinea PigsMyopiaDoxycycline
Hypoxia-responsive Azocalixarene-doxycycline host-guest complex for synergistic myopia control.
Shan He, Pei-Juan Wu, Li Zhang, Jia-Xue Wu, Hou-Li Li, Kun Yi, Qiu-Yun Sun, Zi-Yang Wang, Yu-Xin Yue, Dong-Sheng Guo, Ke Hu, Xiao-Bei Huang, Wen-Juan Wan
Published: 202610.1016/j.jconrel.2025.114586
Abstract
Myopia is one of the most common visual impairments worldwide. Recent studies suggest that scleral hypoxia may act as an early trigger for myopia, initiating oxidative stress (OS) that disrupts extracellular matrix (ECM) remodeling and, in turn, driv…
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