Journal of controlled release : official journal of the Controlled Release SocietyExtracellular VesiclesHumansAnimalsSingle-Chain AntibodiesHEK293 Cells
Rapid extracellular vesicle surface decoration with targeting moieties based on a fluorescein binding single chain variable fragment snorkel.
Marieke Theodora Roefs, Johanna Gamauf, Barbara Kroenigsberger, Alessia Brancolini, Michael W Traxlmayr, Elsa Arcalis, Jaroslaw Jacak, Marcelle van Mechelen, Jean-Paul Prieels, Regina Grillari-Voglauer, Johannes Grillari, Madhusudhan Reddy Bobbili
Published: 202610.1016/j.jconrel.2025.114558
Abstract
Extracellular vesicles (EVs) are cell-derived nanovesicles with promising potential for drug delivery due to their low toxicity and immunogenicity. However, their clinical application is limited by poor targeting to sites of interest. Existing strate…
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