Journal of controlled release : official journal of the Controlled Release SocietyLung NeoplasmsAnimalsNanoparticlesImmunotherapyInterferon-gamma
Pulmonary macrophage-targeted RNAi and mRNA co-delivery via SORT lipid nanoparticles enhances immunotherapy in lung cancer.
Qing Liang, Yue Peng, Linyao Zhao, Zhenlin Yang, Xiaowei Chen, Jinfei Li, Zhiyuan Wu, Kun Chen, Bolun Zhou, Yang Liu, Bin Hu, Chunfeng Qu, Moyan Zhang, Shugeng Gao
Published: 202610.1016/j.jconrel.2025.114519
Abstract
Neoadjuvant immunotherapy has transformed perioperative approaches for resectable non-small cell lung cancer (NSCLC) by stimulating anti-tumor immunity preoperatively; however, approximately 50 % of patients fail to show clinical responses. Single-ce…
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