Journal of controlled release : official journal of the Controlled Release SocietyAnimalsIntervertebral Disc DegenerationCellular SenescenceGoatsMicroalgae
Engineered microalgae-driven gel platform promotes the repairing of senescence-associated intervertebral disc degeneration in rats and goats.
Yao Wang, Tao Xu, Hongchuan Wang, Xiaoyu Cai, Shutao Gao, Weidong Liang, Qiang Deng, Abulizi Yakefu, Maierdan Maimaiti, Chuanhui Xun, Liang Ma, Weibin Sheng
Published: 202610.1016/j.jconrel.2025.114500
Abstract
Intervertebral disc degeneration (IDD), a major cause of low back pain, is closely linked to oxidative stress-mediated inflammation and nucleus pulposus cell (NPC) senescence; however, current clinical treatments fail to effectively target these unde…
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