Journal of controlled release : official journal of the Controlled Release SocietyAnimalsTriple Negative Breast NeoplasmsTumor MicroenvironmentDoxorubicinHydrogels
Boronate-crosslinked hydrogel enables localized chemoimmunotherapy to remodel the immune microenvironment in triple-negative breast cancer.
Rong Liu, Jia-Yi Chen, Cai-Mei Wang, Yan Liang, Wei-Cong Wu, Yuan Shen, Qi Chen, Qun-Yue Wu, Ying Chen
Published: 202610.1016/j.jconrel.2025.114470
Abstract
The efficacy of immunotherapy in triple-negative breast cancer (TNBC) critically depends on the infiltration of functional immune cells within the tumor microenvironment (TME). However, TNBC is frequently characterized by insufficient T cell infiltra…
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