Journal of controlled release : official journal of the Controlled Release SocietyAnimalsMetal-Organic FrameworksTumor Necrosis Factor-alphaInflammatory Bowel DiseasesAntioxidants
An antioxidant metal-organic framework with functional coatings for oral anti-TNF-α antibody delivery in inflammatory bowel disease treatment.
Cheng Chen, Léo Guilbaud, Valentina Marotti, Wunan Zhang, Inês Domingues, Hafsa Yagoubi, Katlijn Vints, Yining Xu, Ana Beloqui
Published: 202610.1016/j.jconrel.2025.114411
Abstract
Oral biomacromolecule delivery is considered a promising alternative for patients who must receive long-term invasive injections, providing better patient compliance. However, it still faces great challenges due to the harsh gastrointestinal environm…
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