Journal of controlled release : official journal of the Controlled Release SocietyAnimalsAdministrationIntranasalRNASmall Interfering
Nasal-to-brain siRNA delivery based on trace amine associated receptor for improving cognitive function.
Liangliang Cai, Shanshan Li, Cheng Wan, Bohui Xu, Haiqin Huang, Lixing Xu
Published: 202510.1016/j.jconrel.2025.114373
Abstract
Gene-based therapies for central nervous system (CNS) disorders face substantial challenges in overcoming the blood-brain barrier (BBB) to effectively target brain tissues. The nasal-to-brain delivery route has gained increasing attention as it bypas…
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