Journal of controlled release : official journal of the Controlled Release SocietyAnimalsMyocardial InfarctionMaleCardiotonic AgentsNanoparticles
Squalene-adenosine nanoparticles enhance cardioprotection in myocardial infarction: Efficacy and mechanistic insights.
Laura Saludas, Elisa Garbayo, Gloria Abizanda, Flavio Dormont, Enrique Santamaría, Felipe Prósper, Patrick Couvreur, María J Blanco-Prieto
Published: 202510.1016/j.jconrel.2025.114369
Abstract
Reperfusion injury following myocardial infarction (MI) poses a significant challenge, as it can exacerbate heart failure despite being the primary treatment. Adenosine is a promising cardioprotective drug, but its rapid degradation in circulation li…
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