Journal of controlled release : official journal of the Controlled Release SocietyDoxorubicinAnimalsCalciumHumansFemale
Hydroxyapatite and doxorubicin-laden nanotherapeutics for effective multimodality cancer treatment boosted via mitochondrial calcium overload.
Yi-Shou Chang, Arjun Sabu, Manoj Kandel, Chun-Liang Lo, Ekta Roy, Lakshminarayan Ramesan, You-Tien Chang, Hsin-Cheng Chiu
Published: 202510.1016/j.jconrel.2025.114368
Abstract
A new nanotherapeutic system comprising palladium-deposited bismuth sulfide (Pd/Bi2S3) nanoparticles (NPs) as the primary component, loaded with doxorubicin (DOX) and coated with PEG-modified hydroxyapatite/mesoporous silica (HAP/MPS) layers, was dev…
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