Journal of controlled release : official journal of the Controlled Release SocietyAnimalsMucocutaneous Lymph Node SyndromeMacrophagesNanoparticlesReactive Oxygen Species
Inflammation-targeted nanoparticles modulate macrophage polarization for coronary therapy in Kawasaki disease.
Zhiwei Chen, Xinyu Di, Heyan Chen, Shengnan Song, Siyi Zhu, Leer Cai, Yuqi Han, Yongshuai Kang, Dingchao Shen, Huirong Huang, Aimin Cai, Hailun Zheng, Qing Yao, Maoping Chu, Ruijie Chen
Published: 202510.1016/j.jconrel.2025.114350
Abstract
Coronary artery lesions are a major complication of Kawasaki disease (KD), where the local microenvironment is marked by excessive oxidative stress and persistent inflammation, presenting significant challenges for effective treatment. M1-polarized m…
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