Journal of controlled release : official journal of the Controlled Release SocietyAnimalsCisplatinLung NeoplasmsSmall Cell Lung CarcinomaCD47 Antigen
Enhancing cisplatin therapy for small cell lung cancer via a dual strategy of combining surufatinib and CD47 blockade.
Kaiming Li, Ziming Lin, Ting Wu, Jintong Zhou, Jie Wu, Yupeng Zhou, Huimin Gao, Ya Lin, Xufeng Chen, Huae Xu, Xiaolin Li
Published: 202510.1016/j.jconrel.2025.114348
Abstract
Small cell lung cancer (SCLC) is a highly lethal malignancy with a < 7 % 5-year survival rate. Platinum-based chemotherapy remains the standard treatment; however, its clinical efficacy is limited. There is an urgent need for new therapeutic strategi…
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