Journal of controlled release : official journal of the Controlled Release SocietySpinal Cord InjuriesAnimalsRatsSprague-DawleyClick Chemistry
Precisely targeting of engineered nanovesicles to implanted scaffolds via click chemistry for microenvironment regulation in acute spinal cord injury.
Xunqi Zhang, Manning Zhu, Jing Guo, Jian Cao, Juanjuan Zheng, Jiahe Wu, Weihang Zhou, Xinchi Jiang, Nan Wang, Jiafu Mu, Tianchen Huang, Jian-Qing Gao
Published: 202510.1016/j.jconrel.2025.114321
Abstract
Spinal cord injury (SCI) requires sufficient and sustained therapeutic intervention for microenvironment regulation in the acute phase. However, systemic drug administration is often ineffective due to non-specific distribution within the damaged spi…
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