Journal of controlled release : official journal of the Controlled Release SocietyAnimalsImmunogenic Cell DeathImmunotherapyMembrane ProteinsNeoplasms
Oxygen-vacancy MoO3-x nanodots induce immunogenic cell death and STING activation for synergistic cancer immunotherapy.
Lifeng Hang, Huijuan Xin, Haijian Li, Laiping Fang, Hua Wen, Jin Fang, Sulian Su, Yiqiang Sun, Wenjiao Wu, Guihua Jiang
Published: 202510.1016/j.jconrel.2025.114319
Abstract
Cancer therapy has been revolutionized by immune checkpoint inhibitor (ICI) therapies, yet the "cold" tumor microenvironment (TME) often resists immunotherapy. Combining immunogenic cell death (ICD) induction with STING (stimulator of interferon gene…
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