Journal of controlled release : official journal of the Controlled Release SocietyRNAMessengerAnimalsLipidsNanocapsules
Surface-engineered robust hybrid lipid nanocapsules: A next-generation nanoplatform for mRNA delivery.
Sunil Kumar Yadava, Anuja Tripathi, Mridula Kabilan, Julie A Champion, Marcus T Cicerone
Published: 202510.1016/j.jconrel.2025.114312
Abstract
Hybrid lipid nanocapsules (hLNCs) represent a promising platform for mRNA delivery with the added benefit of ambient-temperature stabilization. Conventional hLNCs use polyethyleneimine (PEI) to facilitate mRNA binding, cellular uptake, and endosomal…
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