Journal of controlled release : official journal of the Controlled Release SocietyAnimalsNanoparticlesBrainRNAMessenger
Music enhances lipid nanoparticle brain delivery and mRNA transfection in brain cells.
Patricia Mora-Raimundo, Alon Gilon, Haim Kadosh, Yuval Richtman, Mor Sela, Shanny Ackerman, Gal Chen, Ravit Abel, Shaked Kagan, Noga Sharf-Pauker, Or Gigi, Hanan Abumanhal-Masarweh, Utkarsh Tripathi, Malak Saada, Aviram Shemen
Published: 202510.1016/j.jconrel.2025.114301
Abstract
Delivering therapeutic agents to the brain, particularly to neurons, is crucial for advancing treatments for neurological diseases. In this study, we introduce a non-invasive approach using music to enhance the delivery of lipid nanoparticles (LNPs)…
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