Journal of colloid and interface scienceCopperGlucoseHumansChelating AgentsAntineoplastic Agents
A nanoagent based on a supramolecular copper chelator for cancer therapy via copper depletion and glucose deprivation.
Xiaojiao Di, Zelong Chen, Wenhe Feng, Jiajia Sun, Shuang Chao, Zhichao Pei, Yuxin Pei
Published: 202610.1016/j.jcis.2025.139297
Abstract
Given the copper dependence of malignancies, copper depletion therapy has emerged as a promising anticancer strategy. However, its efficacy is hampered by the metabolic adaptability of tumors, which allows tumor cells switch their metabolic phenotype…
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