JACC. Cardiovascular interventionsAtrial AppendageAnimalsAtrial FibrillationDogsHumans
Left Atrial Appendage Occlusion Using a Novel System: Preclinical Evaluation and First-in-Human Experience.
Felix Mahfoud, Christian Ukena, Philip D Adamson, Matthew O'Connor, Matthew Brooks, Lisa-Marie King, John Thompson, Sandeep Panikker
Published: 202510.1016/j.jcin.2025.10.002
Abstract
BACKGROUND: Atrial fibrillation is a major stroke risk, with >90% of thrombi originating from the left atrial appendage (LAA). Oral anticoagulation is effective, but many patients cannot use it long term. Current percutaneous LAA occlusion devices re…
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