Journal of chromatography. B, Analytical technologies in the biomedical and life sciencesAnimalsTandem Mass SpectrometryTissue DistributionDiterpenesMice
Pharmacokinetics and tissue distribution of tripchlorolide in rodents using liquid chromatography tandem mass spectrometry.
Yanping Deng, Lele Zhou, Zhengyan Gu, Zhou Chen
Published: 202510.1016/j.jchromb.2025.124805
Abstract
Tripchlorolide is a promising therapeutic compound with potent pharmacological activity and an improved safety profile compared to triptolide. However, its pharmacokinetics and tissue distribution remain poorly characterized. In this study, we develo…
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