Journal of cystic fibrosis : official journal of the European Cystic Fibrosis SocietyHumansCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorQuinolonesAminophenols
Strategies for the identification of people with cystic fibrosis responsive to CFTR modulator triple combinations.
Pierre-Régis Burgel
Published: 202610.1016/j.jcf.2025.12.019
Abstract
The triple combinations of CFTR modulators, elexacaftor-tezacaftor-ivacaftor and more recently vanzacaftor-tezacaftor-deutivacaftor, have transformed the clinical course of cystic fibrosis (CF). These drug combinations were identified for their abili…
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