Synergistic antitumor effects of recombinant Interleukin-21 and 5-fluorouracil: A novel therapeutic approach against hepatocellular carcinoma.

Interleukin-21 (IL-21) is a pleiotropic cytokine that enhances both humoral and cellular immunity by increasing B-cell proliferation, T-cell effector function, and natural killer (NK) cell cytotoxicity. Studies have demonstrated its potential as an a…

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