The Journal of biological chemistry
Antagonist nanobodies prevent protease inhibition by CD109.
Kathrine Tejlgård Jensen, Ana Viana Almeida, Sanne Rönning, Maximillian Karlander, Nadia Sukusu Nielsen, Ida B Thøgersen, Magdalena Malm, Gregers Rom Andersen, Jan J Enghild, Johan Rockberg, Seandean Lykke Harwood
Published: 202610.1016/j.jbc.2026.111187
Abstract
Cluster of differentiation 109 (CD109) is a cell surface protein found on many human cell types, including keratinocytes, platelets, and T-cells. It is a protease inhibitor of the α-macroglobulin protein superfamily and is reported to affect signalin…
Preview only. Read the full abstract at the source