The Journal of biological chemistry
The amyloidogenic C-Terminal region of TMEM106B modulates lipid membrane biophysical properties: functional and pathological insights.
Mélanie Berbon, Axelle Grélard, Laure Bataille, Nadia El Mammeri
Published: 202610.1016/j.jbc.2026.111175
Abstract
The lysosomal Transmembrane protein 106B (TMEM106B) forms amyloid filaments in the human brain in an age-dependent manner, observed both in neurologically healthy individuals and in patients with neurodegenerative diseases also containing tau, α-synu…
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