The Journal of biological chemistry
ATGL-catalyzed biosynthesis mediates the upregulation of Fatty Acid Hydroxy Fatty Acids (FAHFA) levels in white adipose tissue with fasting.
Anna Santoro, Zhenlong Chen, Andrew T Nelson, Dionicio Siegel, Barbara B Kahn
Published: 202610.1016/j.jbc.2026.111169
Abstract
FAHFAs are a family of bioactive lipids. A subclass of these, Palmitic Acid Hydroxy Stearic Acids (PAHSAs) have anti-inflammatory and anti-diabetic effects. Adipose tissue PAHSA levels are upregulated with increased de novo lipogenesis and fasting, a…
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