The Journal of biological chemistry
IGFBP-6 regulates breast cancer cell cycle progression by promoting exit out of G1.
Francisco J Lariz, Shayla Hernandez, Diana C Bautista-Tovar, Kevin D Houston
Published: 202510.1016/j.jbc.2025.111069
Abstract
While the contribution of the IGF-signaling axis in breast cancer is well-documented, the role of IGFBP-6 in breast carcinogenesis has not been extensively studied. In general, insulin-like growth factor binding protein-6 (IGFBP-6) sequesters insulin…
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