The Journal of biological chemistryHaloferax volcaniiAcetylationLysineArchaeal ProteinsGlycerol
Dynamic acetylation of a conserved lysine impacts glycerol kinase activity and abundance in the haloarchaeon Haloferax volcanii.
Karol M Sanchez, Manasa Addagarla, Heather N Judd, Xin Wang, Julie A Maupin-Furlow
Published: 202610.1016/j.jbc.2025.110960
Abstract
Lysine acetylation is a key regulator of metabolism, but its role in archaeal carbon metabolism remains unclear. In halophilic archaea such as Haloferax volcanii, glycerol kinase (GK, glpK) catalyzes the phosphorylation of glycerol to glycerol-3-phos…
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