Journal of advanced research
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H2S-dependent S-sulfhydration of CTSD.
Xueshi Chen, Xinqi Huang, Yumei An, Cheng Gao, Yuan Gao, Haiyan Shan, Luyang Tao, Xiping Chen, Mingyang Zhang
Published: 202610.1016/j.jare.2026.01.039
Abstract
INTRODUCTION: Traumatic brain injury (TBI) induces complex secondary neuronal death, yet no specific therapeutic strategies are available to ameliorate post-traumatic neurological dysfunction. PANoptosis is a coordinated cell death pathway involving…
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