Journal of advanced research
Synthesis and bioactivity evaluation of isoxazoline scaffolds using heterogeneous photocatalytic (3 + 2) cycloaddition.
Shaochen Li, Bingrui Liu, Xinran Chen, Guangpeng Wang, Chiying Zhang, Shuqing Ma, Yahui Li
Published: 202610.1016/j.jare.2026.01.033
Abstract
INTRODUCTION: The (3 + 2) cycloaddition is a classic method for synthesizing bioactive isoxazoline and isoxazole heterocycles. However, its utility is hampered by a reliance on stoichiometric halogenating oxidants, bases, and multi-step protocols, ge…
Preview only. Read the full abstract at the source