Journal of advanced research
Podocyte-derived exosomes instruct dendritic cell-dependent CD8+ T cell activation and proliferation in renal inflammation.
Bin Qian, Shuya Mao, Yang Chen, Ying Liu, Mingchao Zhang, Dihan Zhu, Ke Zen, Yu Wang, Zhihong Liu, Limin Li
Published: 202610.1016/j.jare.2026.01.032
Abstract
INTRODUCTION: Minimal Change Disease (MCD) represents a prevalent pathological cause of nephrotic syndrome. While podocyte injury is recognized as the direct cause of proteinuria in MCD, aberrant T-cell activation is a key driver of this podocyte dam…
Preview only. Read the full abstract at the source