Journal of advanced research
Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism-from animal models and clinical studies.
Wenkang Gao, Shengqi Yan, Li Zhang, Liuying Chen, Jiake Che, Weiyan Huang, Yue Chen, Ao Liu, Yuanqing Zhu, Ye Yang, Zhong Peng, Chen Tan, Bernd Schnabl, Xiaohua Hou, Ling Yang
Published: 202610.1016/j.jare.2025.12.012
Abstract
BACKGROUND AND AIMS: Drug-induced liver injury (DILI) is a leading cause of acute liver failure. Patients with DILI have disorders of the gut microbiota, yet little is known about the influence of gut microbes on this disease. Herein, we investigated…
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