Journal of advanced research
Exploring the role of β2-microglobulin in the relationship between physical activity and DNAm-predicted PhenoAge: Evidence from a population-based and mice single-cell RNA-sequencing study.
Yanwei You, Jinwei Li, Yang Zhang, Qiyu Liu, Alimjan Ablitip, Yongjie Lao, Jingtong Wang, Kailin Xu, Zhengbang Yao, Yuquan Chen, Xindong Ma
Published: 202510.1016/j.jare.2025.11.047
Abstract
INTRODUCTION: Physical activity (PA) is recognized as a cornerstone of healthy aging, yet the molecular mechanisms linking PA to biological aging remain poorly understood. β2-microglobulin (β2M), an inflammatory and aging biomarker, has emerged as a…
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