Journal of advanced research
Flavonoid-modulated JAK-STAT signaling mitigates malignant transformation and drug resistance in breast tumors: A clinically relevant 3PM-guided innovation.
Peter Kubatka, Mykhailo Huniadi, Andrea Kapinova, Natalia Nosalova, Elizabeth Varghese, Dana Blahutova, Slavomir Hornak, Alexandra Trbolova, Kamil Biringer, Katarina Adamicova, Dasa Cizkova, Dietrich Büsselberg, Olga Golubnitschaja
Published: 202510.1016/j.jare.2025.10.067
Abstract
BACKGROUND: Breast cancer (BC) treatment efficacy is often compromised by tumor cell plasticity and multidrug resistance of multi-factorial origin. Among emerging therapeutic agents, flavonoids - a structurally diverse group of naturally occurring po…
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