Journal of advanced research
Genome-wide CRISPR screen identifies STK11 as a critical regulator of sialic acid clusters important for influenza A virus attachment.
Huimin Sun, Jiahui Zou, Shaoyu Tu, Didan Luo, Rong Xiao, Yue Du, Chuhan Xiong, Shengsong Xie, Hailong Liu, Meilin Jin, Huanchun Chen, Hongbo Zhou
Published: 202510.1016/j.jare.2025.09.059
Abstract
INTRODUCTION: Swine influenza virus (SIV) is a highly contagious respiratory pathogen in pigs that causes substantial economic losses in the pig industry. Importantly, pigs act as "mixing vessels" for diverse influenza A viruses (IAVs), facilitating…
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