Journal of affective disorders
Fatigue in major depression is linked to depression severity, not sleep duration or anterior cingulate cortex neurochemistry.
Samir Batheja, Jie Yang, Yunhan Liao, Kenneth Wengler, Xiang He, Farzana Z Ali, Russell Rozensky, Christine DeLorenzo
Published: 202610.1016/j.jad.2025.121076
Abstract
In major depressive disorder (MDD), it is unclear whether fatigue is a result of poor sleep or depression, and its biological basis is unknown. To explore this, Magnetic Resonance Spectroscopy (1H-MRS) in the anterior cingulate cortex (ACC) was acqui…
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