Journal of affective disorders
Reduced functional connectome uniqueness on the whole brain and network levels as a clinically relevant and reproducible neuroimaging marker in major depressive disorder.
Siti Nurul Zhahara, Yusuke Sudo, Kohei Kurita, Eri Itai, Toshiharu Kamishikiryo, Hitomi Kitagawa, Tokiko Yoshida, Junbing He, Rio Kamashita, Yuko Isobe, Yuki Ikemizu, Koji Matsumoto, Go Okada, Eiji Shimizu, Yoshiyuki Hirano
Published: 202610.1016/j.jad.2025.121073
Abstract
BACKGROUND: Identifying reproducible neurobiological markers for Major Depressive Disorder (MDD) remains challenging due to methodological heterogeneity across neuroimaging studies. Functional connectome (FC) uniqueness, an individual-level metric de…
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