Journal of affective disordersHumansBipolar DisorderMaleFemaleAdult
Data-driven symptom dimensions reveal familial patterns in bipolar disorder.
Katie Scott, Claire O'Donovan, Sandra Meier, Barbara Pavlova, Dean F MacKinnon, James B Potash, Thomas G Schulze, Jennifer Judy, Peter P Zandi, NIMH Genetics Initiative Bipolar Disorder Consortium, Paul Grof, Francis J McMahon, Abraham Nunes, Martin Alda
Published: 202610.1016/j.jad.2025.121060
Abstract
BACKGROUND: Bipolar disorder (BD) is a highly heritable psychiatric illness whose clinical and genetic heterogeneity complicates efforts to identify biologically-relevant subtypes. Traditional categorical approaches often fail to capture the multidim…
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