Journal of affective disorders
Cell-type-specific genetic architecture of postpartum depression: A single-cell Mendelian randomization framework for causal gene discovery.
Ya-Jing Huang, Qiu-Han Xu, Ke-Wei Chen, Huai-Fang Li, Yang Yang
Published: 202510.1016/j.jad.2025.120993
Abstract
BACKGROUND: Postpartum depression (PPD) is a severe psychiatric disorder with complex and multifactorial origins. Although genetic factors have been implicated, the cell-type-specific mechanisms linking genetic variation to disease susceptibility rem…
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