Journal of affective disordersHumansAnhedoniaRewardMaleFemale
Associations between polygenic risk for anhedonia and functional brain activity during reward processing.
Nicholas Schäfer, Swapnil Awasthi, Stephan Ripke, Anna Daniels, Andreas Meyer-Lindenberg, Heike Tost, Andreas Heinz, Henrik Walter, Susanne Erk
Published: 202610.1016/j.jad.2025.120900
Abstract
Anhedonia is an important symptom in major mental disorders and is difficult to address due to a limited understanding of its neurobiological and genetic underpinnings. Here, we investigated the effect of a polygenic risk score (PRS) for anhedonia on…
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